| ¡¡ | Chinese Journal of Computers Full Text |
| Title | DNA Computation Based on Piezoelectric Genosensor |
| Authors | FANG Gang1) ZHANG Yun-Liang1) ZHU Yan1) XU Jin2) |
| Address | 1)(Department of Life Science, Xi¡äan University of Arts and Science, Xi¡äan 430074) 2)(School of Electronics Engineering and Computer Science, Peking University, Beijing 100871) |
| Year | 2008 |
| Issue | No.12(2109¡ª2115) |
| Abstract & Background | Abstract Piezoelectric genosensor is a new type of biosensor, which combines the sensitivity of piezoelectric sensor and DNA hybridization reaction. Compared with traditional gene assay technology, it has the simple construction, label-free feature, time-saving detection speed, and conveniently processed information. When used in DNA computing, compared with conventional DNA chip, its information is easier to process automatically. Thus it can be used conveniently to construct an automatic computing machine. Based on the piezoelectric genosensor and DNA computing theory, a new DNA computing method to solve 0-1 programming problem is proposed in this paper. Compared with other DNA computing methods, it has more significant advantages due to its electric signal output, such as massive parallel of obtaining and managing information, automatically processed signal, and label-free solution detection, etc. It also can overcome some problems, such as solution distinguishing, when carrying out DNA computing with conventional DNA chip. The piezoelectric genosensor can be used as a potential DNA computing chip to construct a DNA computer. Keywords piezoelectric genosensor; DNA chip; DNA computing; 0-1 programming problem; DNA computer |