| ¡¡ | Chinese Journal of Computers Full Text |
| Title | DNA Computing Model with DNAzyme to Control Gene Expression |
| Authors | ZHANG Feng-Yue1) SONG Hai-Gang2) WEN Jun-Hai1) ZHANG Qiang3) LIU Bo4) |
| Address | 1)(Department of Biomedical Engineering, School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081) 2)(Fundamental Research Management Center of Ministry of Science and Technology of China, Beijing 100862) 3)(Liaoning Key Laboratory of Intelligent Information Processing, Dalian University, Dalian, Liaoning 116622) 4)(Chinese Academy of Inspection and Quarantine, Beijing 100029) |
| Year | 2008 |
| Issue | No.12(2097¡ª2102) |
| Abstract & Background | Abstract A molecular computer for logical control of gene expression is an essential research field of DNA computing. In this paper, with its characteristic especially being antisense medication, DNAzyme technique is used in construction of DNA computing model as basis material. Furthermore, a DNA computing model is designed to control H-ras gene expression, and this model also has potential to control other over expressed genes. Benefited from the massive parallelism and intelligence feature of DNA computing, this model explores further application of DNA computing to control of gene expression. Keywords DNA computing; DNAzyme; control of gene expression |